[Urinary urease activity in urolithiasis patients]. / Ureaznaia aktivnost' mochi u bol'nykh mochekamennoi bolezn'iu.

Urease activity (UA) and the ability of the urine to form crystals (AFC) were assessed in the urine from 149 urolithiasis patients and 11 healthy controls. Patients with primary uroliths had high UA and AFC in 17-18% of the cases, in recurrent urolithiasis this percentage was 29-35%. The speed of phosphate and oxalate crystals formation as well as formation of renal calculus correlated with UA and UA levels. Thus, UA and AFC may be employed as criteria in prognostication of the duration of phosphate and oxalate lithogenesis.

[Role of lipids in adaptive responses of the body to extreme exposure]. / Rol' lipidov v adaptationnykh reaktsiiakh organizma na ékstremal'nye vozdeistviia.

Experiments were conducted on 250 male albino rats to study the blood serum lipid spectrum in total-body dehydration, adrenalin-induced necroses of the myocardium, under the effect of transport noise with an equivalent level of 80-95 decibels and ultrashort-wave range electromagnetic field of 5-6 V/m intensity. In the early stages of exposure to the effect of extreme factors the change in lipid metabolism was monotypic in character and was manifested by hypercholesterolemia at the cost of the free fraction, increase of the level of triglycerides, free fatty acids and activity of lecithin-cholesterol acyltransferase, and reduction of the content of total phospholipids and disorders of their composition. These changes are associated with disturbed neurohumoral regulation and reflect the unspecific response of the organism to damage in the form of mobilization of lipids from the depot and switching metabolism from the carbohydrate to the lipid type.

[Changes in the phospholipid-phospholipid ratios and the enzyme activity of antioxidant protection in the rat lung during dehydration]. / Izmenenie fosfolipid-fosfolipidnykh sootnoshenii i aktivnost' fermentov antioksidantnoi zashchity v legkikh krys pri degidratatsii.

It was established that water deprivation during 3, 6, 9 days caused a distinct decrease in phospholipid level and disturbances of phospholipid composition in the rat lung tissue. It was accompanied by alterations in the activity of antioxidant defense system enzymes (superoxide dismutase, glutathione peroxidase, glutathione reductase, catalase, glucose-6-phosphate dehydrogenase). These data are indicative of lipid peroxidation intensification in the rat lungs during water deprivation.

[Phospholipid composition of various tissues of rats during dehydration]. / Fosfolipidnyi sostav razlichnykh tkanei krys pri obezvozhivanii organizma.

It was established that water deprivation led to dissimilar disturbances of phospholipid composition in rat blood serum and tissues. Content of individual phospholipids altered depending on their susceptibility to peroxidation. The role of the alterations observed in membrane destabilization, inactivation of membrane-bound enzymes, intensification of lipid peroxidation and other disorders are discussed.